Sequence and organization of large subunit rRNA genes from the extrachromosomal 35 kb circular DNA of the malaria parasite Plasmodium falciparum.

@article{Gardner1993SequenceAO,
  title={Sequence and organization of large subunit rRNA genes from the extrachromosomal 35 kb circular DNA of the malaria parasite Plasmodium falciparum.},
  author={Malcolm J. Gardner and Jean E. Feagin and Daphne J. Moore and Kaveri Rangachari and Donald H. Williamson and Robert J. M. Wilson},
  journal={Nucleic acids research},
  year={1993},
  volume={21 5},
  pages={1067-71}
}
The malaria parasite Plasmodium falciparum carries an extrachromosomal 35 kb circular DNA molecule of unknown provenance. A striking feature of the circle is a palindromic sequence of genes for subunit rRNAs and several tRNAs, spanning ca. 10.5 kb. The palindrome has an intriguing resemblance to the inverted repeat of plastid genomes, and the sequence and putative secondary structure of the malarial large subunit (LSU) rRNA described in this report were used as the basis of a phylogenetic study… CONTINUE READING

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