Sequence and expression of Sox-18 encoding a new HMG-box transcription factor.

@article{Dunn1995SequenceAE,
  title={Sequence and expression of Sox-18 encoding a new HMG-box transcription factor.},
  author={Tasha L. Dunn and Lesley Mynett-Johnson and E. M. Wright and Brett M Hosking and Peter Koopman and George E. O. Muscat},
  journal={Gene},
  year={1995},
  volume={161 2},
  pages={223-5}
}
The newly identified Sox gene family (Sry-like HMG-box gene) is characterized by a conserved DNA sequence encoding a domain of approx. 80 amino acids (aa) which is responsible for sequence-specific DNA binding. The first member isolated, the mammalian Y-linked testis-determining gene, Sry, is necessary and sufficient for male development. We report here the… CONTINUE READING