Sequence and expression analyses of KIX domain proteins suggest their importance in seed development and determination of seed size in rice, and genome stability in Arabidopsis

@article{Thakur2013SequenceAE,
  title={Sequence and expression analyses of KIX domain proteins suggest their importance in seed development and determination of seed size in rice, and genome stability in Arabidopsis},
  author={Jitendra Kumar Thakur and Pinky Agarwal and Swarup Kumar Parida and Deepak Bajaj and Richa Pasrija},
  journal={Molecular Genetics and Genomics},
  year={2013},
  volume={288},
  pages={329-346}
}
The KIX domain, which mediates protein–protein interactions, was first discovered as a motif in the large multidomain transcriptional activator histone acetyltransferase p300/CBP. Later, the domain was also found in Mediator subunit MED15, where it interacts with many transcription factors. In both proteins, the KIX domain is a target of activation domains of diverse transcription activators. It was found to be an essential component of several specific gene-activation pathways in fungi and… CONTINUE READING

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