Sequence and environmental effects on the self-assembly of DNA oligomers possessing GxT2Gy segments.

@article{Marotta1996SequenceAE,
  title={Sequence and environmental effects on the self-assembly of DNA oligomers possessing GxT2Gy segments.},
  author={S P Marotta and P A Tamburri and Richard D Sheardy},
  journal={Biochemistry},
  year={1996},
  volume={35 32},
  pages={10484-92}
}
It is well-known that DNA oligomers possessing contiguous guanine bases can assume non-Watson-Crick type structures through the formation of four-stranded species. The architecture of these four-stranded structures is highly dependent upon the sequence of the DNA and the conditions (e.g., buffer, pH, ionic strength, cations present, and temperature) under which the DNA is prepared. This lab has previously reported the self-assembly of DNA oligomers of sequence C4T4G4T1-4G4 into multistranded… CONTINUE READING
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