Sequence and comparative genomic analysis of lactococcal bacteriophages jj50, 712 and P008: evolutionary insights into the 936 phage species.

@article{Mahony2006SequenceAC,
  title={Sequence and comparative genomic analysis of lactococcal bacteriophages jj50, 712 and P008: evolutionary insights into the 936 phage species.},
  author={Jennifer Mahony and H{\'e}l{\`e}ne Deveau and Stephen Mc Grath and Marco Ventura and Carlos Canchaya and Sylvain Moineau and Gerald F. Fitzgerald and Douwe van Sinderen},
  journal={FEMS microbiology letters},
  year={2006},
  volume={261 2},
  pages={253-61}
}
The complete genome sequences of three lactococcal 936-type bacteriophages, 712, jj50 and P008, were determined. Comparative genomic analysis of these phages with the previously sequenced 936-type phages, sk1 and bIL170, reveals a strict conservation of the overall genetic organization of this geographically diverse phage group. Genetic divergence was mainly observed in the early expressed region of the phage genomes, where a number of deletions, exchanges and insertions appear to have occurred… CONTINUE READING

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