Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products.

@article{Galleni1988SequenceAC,
  title={Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products.},
  author={Moreno Galleni and Frederik Lindberg and Staffan J. Normark and Stewart J. Cole and Nadine Honor{\'e} and Bernard Joris and Jr. J. M. Frere},
  journal={The Biochemical journal},
  year={1988},
  volume={250 3},
  pages={
          753-60
        }
}
The sequences of three Enterobacter cloacae ampC beta-lactamase genes have been determined. The deduced amino acid sequences are very similar: out of a total of 361 residues, only eight positions were found to be variable, and several mutations yielded residues with very similar properties. The kinetic properties of two of the enzymes were not significantly different. The three enzymes also exhibited a high degree of homology (greater than 70%) with the ampC beta-lactamases of Escherichia coli… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 47 CITATIONS

Similar Papers

Loading similar papers…