Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk


PURPOSE To investigate how potentially functional genetic variants are coinherited on each of four common complement factor H (CFH) and CFH-related gene haplotypes and to measure expression of these genes in eye and liver tissues. METHODS We sequenced the CFH region in four individuals (one homozygote for each of four common CFH region haplotypes) to… (More)
DOI: 10.1167/iovs.15-18744


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