Sequence analysis using logic regression.

  title={Sequence analysis using logic regression.},
  author={Charles L. Kooperberg and Ingo Ruczinski and Michael L. Leblanc and Li Hsu},
  journal={Genetic epidemiology},
  volume={21 Suppl 1},
Logic Regression is a new adaptive regression methodology that attempts to construct predictors as Boolean combinations of (binary) covariates. In this paper we use this algorithm to deal with single-nucleotide polymorphism (SNP) sequence data. The predictors that are found are interpretable as risk factors of the disease. Significance of these risk factors is assessed using techniques like cross-validation, permutation tests, and independent test sets. These model selection techniques remain… CONTINUE READING

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