Sequence analysis of zebrafish chondromodulin-1 and expression profile in the notochord and chondrogenic regions during cartilage morphogenesis

@article{Sachdev2001SequenceAO,
  title={Sequence analysis of zebrafish chondromodulin-1 and expression profile in the notochord and chondrogenic regions during cartilage morphogenesis},
  author={Sherri Weiss Sachdev and Uwe H Dietz and Yusuke Oshima and Michael Ricardo Lang and Ela W. Knapik and Yoshio Hiraki and Chisa Shukunami},
  journal={Mechanisms of Development},
  year={2001},
  volume={105},
  pages={157-162}
}
Chondromodulin-I (ChM-I) is suggested in higher vertebrate systems to function as a key regulatory protein for cartilage development. To further understand the process of chondrogenesis and the function of ChM-I, we have cloned the zebrafish cDNA for chondromodulin-1 (chm1) and have mapped the chm1 gene locus. The expression profile of chm1 was determined during zebrafish embryonic development and compared to that of type II collagen (col2a1). Maternal chm1 transcripts were detected before… CONTINUE READING
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