Sequence analysis of the cis-regulatory regions of the bithorax complex of Drosophila.

@article{Lewis1995SequenceAO,
  title={Sequence analysis of the cis-regulatory regions of the bithorax complex of Drosophila.},
  author={Edward B. Lewis and John D. Knafels and David R. Mathog and Susan E. Celniker},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 18},
  pages={8403-7}
}
The bithorax complex (BX-C) of Drosophila, one of two complexes that act as master regulators of the body plan of the fly, has now been entirely sequenced and comprises approximately 315,000 bp, only 1.4% of which codes for protein. Analysis of this sequence reveals significantly overrepresented DNA motifs of unknown, as well as known, functions in the non-protein-coding portion of the sequence. The following types of motifs in that portion are analyzed: (i) concatamers of mono-, di-, and… CONTINUE READING
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