Sequence analysis of bacteriophage T4 DNA packaging/terminase genes 16 and 17 reveals a common ATPase center in the large subunit of viral terminases.

@article{Mitchell2002SequenceAO,
  title={Sequence analysis of bacteriophage T4 DNA packaging/terminase genes 16 and 17 reveals a common ATPase center in the large subunit of viral terminases.},
  author={Michael S. Mitchell and Shigenobu Matsuzaki and Shosuke Imai and Venigalla B Rao},
  journal={Nucleic acids research},
  year={2002},
  volume={30 18},
  pages={
          4009-21
        }
}
Phage DNA packaging is believed to be driven by a rotary device coupled to an ATPase 'motor'. Recent evidence suggests that the phage DNA packaging motor is one of the strongest force-generating molecular motors reported to date. However, the ATPase center that is responsible for generating this force is unknown. In order to identify the DNA translocating ATPase, the sequences of the packaging/terminase genes of coliphages T4 and RB49 and vibriophages KVP40 and KVP20 have been analyzed… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 44 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 70 REFERENCES

Phylogeny of the major head and tail genes of the wide-ranging T4-type bacteriophages

  • F. TeÂtart, C. Desplats, M. Kutateladze, C. Monod, H. W. Ackermann, H. M. Krisch
  • J. Bacteriol.,
  • 2001

Similar Papers

Loading similar papers…