Sequence analysis of EBV immune evasion gene BNLF2a in EBV associated tumors and healthy individuals from nasopharyngeal carcinoma endemic and non-endemic regions of China.

@article{Liu2015SequenceAO,
  title={Sequence analysis of EBV immune evasion gene BNLF2a in EBV associated tumors and healthy individuals from nasopharyngeal carcinoma endemic and non-endemic regions of China.},
  author={Song Liu and Xiaofeng Wang and Jun Shu and Zhenzhen Zhao and Zhifu Sun and Bing Jun Luo},
  journal={Journal of medical virology},
  year={2015},
  volume={87 11},
  pages={1946-52}
}
BNLF2a is an Epstein-Barr virus (EBV) immune evasion gene. Its protein is located in the endoplasmic reticulum (ER) membrane, and can inhibit the antigen transporting function of TAP, thereby perturbing the immune response to EBV in lytic and prelatent phase. In order to explore whether the polymorphism of BNLF2a gene has a role in different types of EBV… CONTINUE READING