Sequence analysis and characterization of a transferable hybrid plasmid encoding multidrug resistance and enabling zoonotic potential for extraintestinal Escherichia coli.

@article{Johnson2010SequenceAA,
  title={Sequence analysis and characterization of a transferable hybrid plasmid encoding multidrug resistance and enabling zoonotic potential for extraintestinal Escherichia coli.},
  author={Timothy J. Johnson and Dianna M Jordan and Subhashinie Kariyawasam and Adam L. Stell and Nathan P Bell and Yvonne M. Wannemuehler and Claudia Fern{\'a}ndez Alarc{\'o}n and Ganwu Li and Kelly Anne Tivendale and Catherine Mary Logue and Lisa Kay Nolan},
  journal={Infection and immunity},
  year={2010},
  volume={78 5},
  pages={1931-42}
}
ColV plasmids of extraintestinal pathogenic Escherichia coli (ExPEC) encode a variety of fitness and virulence factors and have long been associated with septicemia and avian colibacillosis. These plasmids are found significantly more often in ExPEC, including ExPEC associated with human neonatal meningitis and avian colibacillosis, than in commensal E. coli. Here we describe pAPEC-O103-ColBM, a hybrid RepFIIA/FIB plasmid harboring components of the ColV pathogenicity island and a multidrug… CONTINUE READING

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