Sequence TTKF ↓ QE defines the site of proteolytic cleavage in Mhp683 protein, a novel glycosaminoglycan and cilium adhesin of Mycoplasma hyopneumoniae.

@article{Bogema2011SequenceT,
  title={Sequence TTKF ↓ QE defines the site of proteolytic cleavage in Mhp683 protein, a novel glycosaminoglycan and cilium adhesin of Mycoplasma hyopneumoniae.},
  author={Daniel Ross Bogema and Nichollas E. Scott and Matthew P Padula and Jessica Leigh Tacchi and Benjamin Bernard Armando Raymond and Cheryl Jenkins and Stuart James Cordwell and F. Chris Minion and Mark J Walker and Steven Philip Djordjevic},
  journal={The Journal of biological chemistry},
  year={2011},
  volume={286 48},
  pages={41217-29}
}
Mycoplasma hyopneumoniae colonizes the ciliated respiratory epithelium of swine, disrupting mucociliary function and inducing chronic inflammation. P97 and P102 family members are major surface proteins of M. hyopneumoniae and play key roles in colonizing cilia via interactions with glycosaminoglycans and mucin. The p102 paralog, mhp683, and homologs in strains from different geographic origins encode a 135-kDa pre-protein (P135) that is cleaved into three fragments identified here as P45(683… CONTINUE READING
Highly Cited
This paper has 43 citations. REVIEW CITATIONS
17 Citations
3 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-3 of 3 references

Barchia, I.,Walker,M

  • J. Wilton, C. Jenkins, +5 authors A. Connolly
  • J., andDjord- jevic, S. P. (2009)Mol. Microbiol
  • 2009
Highly Influential
10 Excerpts

Proteolytic Cleavage Sites in Mhp683 41228 JOURNAL OF BIOLOGICAL CHEMISTRY

  • C R., C. C. Staats, +6 authors A. Zaha
  • DECEMBER
  • 2011
2 Excerpts

Similar Papers

Loading similar papers…