Sequence-Dependent Interfacial Adsorption and Permeation of Dipeptides across Phospholipid Membranes.

Abstract

We investigate permeation of three blocked dipeptides with different side chain polarity across a phospholipid membrane and their behavior at the water-membrane interface by way of molecular dynamics simulations. Hydrophilic serine-serine dipeptide is found to desorb from the interface to aqueous phase, whereas hydrophobic phenylalanine-leucine and… (More)
DOI: 10.1021/acs.jpcb.7b08238

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Cite this paper

@article{Wei2017SequenceDependentIA, title={Sequence-Dependent Interfacial Adsorption and Permeation of Dipeptides across Phospholipid Membranes.}, author={Chenyu Wei and Andrew Pohorille}, journal={The journal of physical chemistry. B}, year={2017}, volume={121 42}, pages={9859-9867} }