Sequence Dependence of Viral RNA Encapsidation.


We develop a Flory mean-field theory for viral RNA (vRNA) molecules that extends the current RNA folding algorithms to include interactions between different sections of the secondary structure. The theory is applied to sequence-selective vRNA encapsidation. The dependence on sequence enters through a single parameter: the largest eigenvalue of the Kramers… (More)
DOI: 10.1021/acs.jpcb.6b01964


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