Sequence Dependence of Viral RNA Encapsidation.


We develop a Flory mean-field theory for viral RNA (vRNA) molecules that extends the current RNA folding algorithms to include interactions between different sections of the secondary structure. The theory is applied to sequence-selective vRNA encapsidation. The dependence on sequence enters through a single parameter: the largest eigenvalue of the Kramers… (More)
DOI: 10.1021/acs.jpcb.6b01964


Cite this paper

@article{Kelly2016SequenceDO, title={Sequence Dependence of Viral RNA Encapsidation.}, author={Joshua T. Kelly and Alexander Y. Grosberg and Robijn Bruinsma}, journal={The journal of physical chemistry. B}, year={2016}, volume={120 26}, pages={6038-50} }