Sequence, annotation and developmental expression of the sea urchin Ca(2+) -ATPase family.

@article{Gunaratne2007SequenceAA,
  title={Sequence, annotation and developmental expression of the sea urchin Ca(2+) -ATPase family.},
  author={H Jayantha Gunaratne and Victor D. Vacquier},
  journal={Gene},
  year={2007},
  volume={397 1-2},
  pages={67-75}
}
Whole genome sequence data permit the study of protein families regulating cellular homeostasis during development. Here we present a study of the sea urchin Ca(2+)-ATPases made possible by the Sea Urchin Genome Sequencing Project. This is of potential interest because adult sea urchins, their gametes and embryos live in the relatively high Ca(2+) concentration of 10 mM. Three Ca(2+)-ATPases regulate Ca(2+) levels in animal cells: plasma membrane Ca(2+)-ATPase (PMCA), sarcoplasmic/endoplasmic… CONTINUE READING