Septic shock; current pathogenetic concepts from a clinical perspective.

  title={Septic shock; current pathogenetic concepts from a clinical perspective.},
  author={Adelais G Tsiotou and George H. Sakorafas and George T Anagnostopoulos and J. P. Bramis},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  volume={11 3},
Sepsis is an infection-induced syndrome characterized by a generalized inflammatory state and represents a frequent complication in the surgical patient. The normal reaction to infection involves a series of complex immunologic processes. A potent, complex immunologic cascade ensures a prompt protective response to microbial invasion in humans. Although activation of the immune system during microbial invasion is generally protective, septic shock develops in a number of patients as a… CONTINUE READING
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