Sepsis syndromes: understanding the role of innate and acquired immunity.

@article{Oberholzer2001SepsisSU,
  title={Sepsis syndromes: understanding the role of innate and acquired immunity.},
  author={Andreas L. Oberholzer and Caroline Oberholzer and Lyle L. Moldawer},
  journal={Shock},
  year={2001},
  volume={16 2},
  pages={
          83-96
        }
}
An intact innate and acquired immune response are essential for defeating systemic microbial infections. Recognition molecules, inflammatory cells, and the cytokines they produce are the principal means for host tissues to recognize invading microbes and to initiate intercellular communication between the innate and acquired immune systems. However, activation of host innate immunity may also occur in the absence of microbial recognition, through expression of internal "danger" signals produced… CONTINUE READING
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