Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group.

@article{Bone1989SepsisSA,
  title={Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group.},
  author={Roger C. Bone and Charles J. Fisher and Terry P. Clemmer and Gus J Slotman and Craig Metz and Robert A. Balk},
  journal={Critical care medicine},
  year={1989},
  volume={17 5},
  pages={389-93}
}
The sepsis syndrome represents a systemic response to infection and is defined as hypothermia (temperature less than 96 degrees F) or hyperthermia (greater than 101 degrees F), tachycardia (greater than 90 beat/min), tachypnea (greater than 20 breath/min), clinical evidence of an infection site and with at least one end-organ demonstrating inadequate perfusion or dysfunction expressed as poor or altered cerebral function, hypoxemia (PaO2 less than 75 torr), elevated plasma lactate, or oliguria… CONTINUE READING
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