Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest.

Abstract

OBJECTIVES To evaluate whether the up-regulation in sepsis-induced gut epithelial apoptosis is balanced by an increase in intestinal proliferation and to assess mechanisms affecting the gut's regenerative response to overwhelming infection. DESIGN Prospective, randomized, controlled study. SETTING Animal laboratory in a university medical center… (More)

Topics

Cite this paper

@article{Coopersmith2003SepsisFP, title={Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest.}, author={Craig M. Coopersmith and Paul E Stromberg and Christopher G. Davis and W. Michael Dunne and Daniel M Amiot and Irene E. Karl and Richard S. Hotchkiss and Timothy G. Buchman}, journal={Critical care medicine}, year={2003}, volume={31 6}, pages={1630-7} }