Sepiapterin reverses the changes in gastric nNOS dimerization and function in diabetic gastroparesis.

Abstract

BACKGROUND We have demonstrated previously that in vivo supplementation of tetrahydrobiopterin (BH₄); a co-factor for neuronal nitric oxide synthase (nNOS) significantly restored delayed gastric emptying and attenuated nitrergic relaxation in diabetic rat. In this study, we have investigated whether supplementation of sepiapterin (SEP), a precursor for BH… (More)
DOI: 10.1111/j.1365-2982.2010.01588.x

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@article{Gangula2010SepiapterinRT, title={Sepiapterin reverses the changes in gastric nNOS dimerization and function in diabetic gastroparesis.}, author={Pandu R. R. Gangula and Sutapa Mukhopadhyay and Pankaj Jay Pasricha and Kalpana Ravella}, journal={Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society}, year={2010}, volume={22 12}, pages={1325-31, e351-2} }