Separation of two phenotypically similar cell types via a single common marker in microfluidic channels.

@article{Vickers2012SeparationOT,
  title={Separation of two phenotypically similar cell types via a single common marker in microfluidic channels.},
  author={Dwayne Vickers and Emma J. Chory and S R Keshava Murthy},
  journal={Lab on a chip},
  year={2012},
  volume={12 18},
  pages={3399-407}
}
To isolate clinically and biologically relevant cell types from a heterogeneous population, fluorescent or magnetic tagging together with knowledge of surface biomarker profiles represents the state of the art. To date, it remains exceedingly difficult to separate phenotypically and physically similar cell types from a mixed population. We report a microfluidic platform engineered to separate two highly similar cell types using a single antibody by taking advantage of subtle variations in… CONTINUE READING