Separation of self from non-self in the complement system.


The alternative complement pathway is a self-contained and independent recognition and effector pathway that evolved to protect the host from microbes. As such, it must separate self from non-self. Via low grade continuous turnover (tickover) of the pivotal C3 component, the alternative complement pathway is always on guard to defend the host. Activated C3… (More)
DOI: 10.1016/0167-5699(87)90167-8


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.