Separation of racemic 2,4-dinitrophenyl amino acids on 9-O-(phenyloxycarbonyl)quinine-bonded carbon-clad zirconia in reversed-phase liquid chromatography.

@article{Park2004SeparationOR,
  title={Separation of racemic 2,4-dinitrophenyl amino acids on 9-O-(phenyloxycarbonyl)quinine-bonded carbon-clad zirconia in reversed-phase liquid chromatography.},
  author={Jung Hag Park and Joon Woo Lee and Sang Hyun Kwon and Jin Soon Cha and Peter W. Carr and Clayton V. McNeff},
  journal={Journal of chromatography. A},
  year={2004},
  volume={1050 2},
  pages={
          151-7
        }
}
Zirconia is known to be one of the best materials for the chromatographic support due to its excellent chemical, thermal, and mechanical stability. In this work, we report preparation and use of 9-O-(phenyloxycarbonyl)quinine-bonded carbon-clad zirconia (QNCZ) as a chiral stationary phase (CSP) for separation of N-(2,4-dinitrophenyl) (DNP)-amino acids (AAs) enantiomers in reversed-phase liquid chromatography. Retention and enantioselectivity of the QNCZ CSP were compared with those of quinine 3… Expand
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