Separation of enantiomers of 1a,2,7,7a-tetrahydro-3-methoxynaphtha-(2,3b)-oxirane by liquid chromatography: laboratory-scale elution chromatography and modelling of simulated moving bed

@article{Rodrigues1995SeparationOE,
  title={Separation of enantiomers of 1a,2,7,7a-tetrahydro-3-methoxynaphtha-(2,3b)-oxirane by liquid chromatography: laboratory-scale elution chromatography and modelling of simulated moving bed},
  author={A. Rodrigues and Z. P. Lu and J. Loureiro and L. Pais},
  journal={Journal of Chromatography A},
  year={1995},
  volume={702},
  pages={223-231}
}
  • A. Rodrigues, Z. P. Lu, +1 author L. Pais
  • Published 1995
  • Chemistry
  • Journal of Chromatography A
  • Abstract The separation of enantiomers of 1 a ,2,7,7 a -tetrahydro-3-methoxynaphtha-(2,3 b )-oxirane (Sandoz epoxide) on cellulose triacetate HPLC columns was investigated on the laboratory scale. The performance of the columns was calculated by HEPT measurements and the slopes of the adsorption equilibrium isotherms and effective diffusivities were calculated from elution chromatographic experiments. Multi-component adsorption equilibrium isotherms were calculated from single isotherms by… CONTINUE READING
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