Separation of conformational isomers in the 5,10-secocardenolide series. I.


A rare case of separable conformational isomers in the 5,10-diketo-5,10-secocardenolide series has been found. Thus, the periodate oxidation of 10β-hydroxy-19-norperiplogenin has given 3β,14β-dihydroxy-5,10-diketocard-19-nor-5,10-seco-20(22)-enolides which in fact consist of a mixture of conformers formed as the result of the inversion of the AB ring. A… (More)
DOI: 10.1007/BF00574253


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