Separation of cancer cells from a red blood cell suspension using inertial force.

@article{Tanaka2012SeparationOC,
  title={Separation of cancer cells from a red blood cell suspension using inertial force.},
  author={Tatsuya Tanaka and Takuji Ishikawa and Keiko Numayama-Tsuruta and Yohsuke Imai and Hironori Ueno and Noriaki Matsuki and Takami Yamaguchi},
  journal={Lab on a chip},
  year={2012},
  volume={12 21},
  pages={
          4336-43
        }
}
The circulating tumor cell (CTC) test has recently become popular for evaluating prognosis and treatment efficacy in cancer patients. The accuracy of the test is strongly dependent on the precision of the cancer cell separation. In this study, we developed a multistage microfluidic device to separate cancer cells from a red blood cell (RBC) suspension using inertial migration forces. The device was able to effectively remove RBCs up to the 1% hematocrit (Hct) condition with a throughput of 565… 
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