Separation of Pharmaceutical Enantiomers using Supercritical Fluid Technology

  title={Separation of Pharmaceutical Enantiomers using Supercritical Fluid Technology},
  author={Bhupinder Singh Sekhon},
The use of supercritical fluids as chromatographic mobile phases provides rapid separations with high efficiency, favoring their use in enantioselective separations. Supercritical fluid technology (SFC) is a versatile tool in the purification, enantioseparation and large-scale production of enantiomers of pharmaceuticals over comparable liquid chromatographic methods and is gaining popularity in pharmaceutical industry. The addition of organic modifiers and additives to the supercritical carbon… CONTINUE READING

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Showing 1-10 of 26 references

Chiral separation of ibuprofen by supercritical fluid chromatography

  • H Soonkoo, R Kyungho
  • Chinese J Chem Eng
  • 2005

Application of supercritical fluid extraction for fractionation of enantiomers

  • E Székely, B Simándi, R Illés, P Molnár, I Gebefügi, I Kmecz
  • J Supercrit Fluids
  • 2004

Enantioselective supercritical fluid extraction from racemic mixtures by use of chiral selectors

  • R Bauza, A Ríos, M. Valcarcel
  • Separ Sci Technol
  • 2004

Resolution of N-methylamphetamine enantiomers with tartaric acid derivatives by supercritical fluid extraction

  • I Kmecz, B Simándi, E Székely, E. Fogassy
  • Tetrahedron: Asymmetr
  • 2004

Trends in the development of chiral drugs

  • H Craner, E Groner, L Levy, I. Agranat
  • Drug Discov Today
  • 2004

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