Separation of Pharmaceutical Enantiomers using Supercritical Fluid Technology

@inproceedings{Sekhon2003SeparationOP,
  title={Separation of Pharmaceutical Enantiomers using Supercritical Fluid Technology},
  author={Bhupinder Singh Sekhon},
  year={2003}
}
The use of supercritical fluids as chromatographic mobile phases provides rapid separations with high efficiency, favoring their use in enantioselective separations. Supercritical fluid technology (SFC) is a versatile tool in the purification, enantioseparation and large-scale production of enantiomers of pharmaceuticals over comparable liquid chromatographic methods and is gaining popularity in pharmaceutical industry. The addition of organic modifiers and additives to the supercritical carbon… CONTINUE READING

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