Separation of Nadolol Stereoisomers Using Chiralpak IA Chiral Stationary Phase.

@article{Arafah2016SeparationON,
  title={Separation of Nadolol Stereoisomers Using Chiralpak IA Chiral Stationary Phase.},
  author={Rami S Arafah and Ant{\'o}nio E Ribeiro and A. Rodrigues and L. Pais},
  journal={Chirality},
  year={2016},
  volume={28 5},
  pages={
          399-408
        }
}
  • Rami S Arafah, António E Ribeiro, +1 author L. Pais
  • Published 2016
  • Chemistry, Medicine
  • Chirality
  • Chiralpak IA adsorbent is used for both analytical and preparative chromatographic separation of nadolol stereoisomers. The results include a complete screening of the mobile phase composition for both the baseline resolution of all four nadolol stereoisomers (analytical separation) and the simulated moving bed (SMB) pseudo-binary separation of the most retained stereoisomer. The experimental results show that analytical baseline resolution of nadolol stereoisomers can be achieved using alcohol… CONTINUE READING
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