Separation methods for antiviral phosphorus-containing drugs.


Among antiviral drugs, phosphorus-containing compounds, foscarnet and cidofovir, present adverse effects including renal toxicity. Since their main therapeutic target is the treatment of CMV retinitis, which needs lifelong maintenance therapy, accurate analytical methods are required for drug monitoring. According to the high hydrophilic property of the two… (More)


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@article{Ba2001SeparationMF, title={Separation methods for antiviral phosphorus-containing drugs.}, author={Boubakar B. Ba and M. C. Saux}, journal={Journal of chromatography. B, Biomedical sciences and applications}, year={2001}, volume={764 1-2}, pages={349-62} }