Separation and quantitative determination of sesquiterpene lactones in Lindera aggregata (wu-yao) by ultra-performance LC-MS/MS.

@article{Wu2010SeparationAQ,
  title={Separation and quantitative determination of sesquiterpene lactones in Lindera aggregata (wu-yao) by ultra-performance LC-MS/MS.},
  author={Yongjiang Wu and Yunliang Zheng and Xuesong Liu and Zheng Han and Yiping Ren and Lishe Gan and Chang-xin Zhou and Lian-jun Luan},
  journal={Journal of separation science},
  year={2010},
  volume={33 8},
  pages={
          1072-8
        }
}
An ultra-performance LC in combination with MS/MS method was established to evaluate the quality of wu-yao (the dried root of Lindera aggregata (Sims) Kosterm. (Lauraceae)) through simultaneous quantitation of five sesquiterpene lactones, linderagalactone D (1), linderagalactone C (2), hydroylindestenolide (3), neolinderalactone (4) and linderane (5). All compounds were separated on a Waters Acquity ultra-performance LC HSS T3 column (2.1 mm x 100 mm, 1.8 microm particle size) with linear… Expand
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