Separation and quantitation of nitrobenzenes and their reduction products nitroanilines and phenylenediamines by reversed-phase high-performance liquid chromatography

@article{Reddy1993SeparationAQ,
  title={Separation and quantitation of nitrobenzenes and their reduction products nitroanilines and phenylenediamines by reversed-phase high-performance liquid chromatography},
  author={T. Reddy and B. Wiechman and E. Lin and L. Chang and M. K. Smith and F. Daniel and G. Reddy},
  journal={Journal of Chromatography A},
  year={1993},
  volume={655},
  pages={331-335}
}
Abstract A reversed-phase high-performance liquid chromatographic method for the separation and quantitation of a mixture consisting of nitrobenzene, dinitrobenzene isomers, 1,3,5-trinitrobenzene and their reduction products: aniline, nitroanilines and phenylenediamines has been developed. The method is sensitive and highly reproducible. The mixture is resolved on a Zorbax C 8 column with 0.1% triethylamine and methanol as the mobile phase. The detection limits for individual chemicals at 254… Expand
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References

SHOWING 1-10 OF 14 REFERENCES
High-performance liquid chromatography of nitroaromatic compounds on an N-propylaniline bonded stationary phase
Abstract N-Propylanilinetrimethoxysilane was reacted with 10 μm silica and the resulting bonded stationary phase was assessed for the liquid chromatographic separation of nitro and polynitroaromaticExpand
Separation of mixtures of 2,4,6-trinitrotoluene reduction products with liquid chromatography
Abstract A high-performance liquid Chromatographic procedure is described for the partial separation of 2,4,6-trinitrotoluene and eight reduction products. A methanol gradient effectively separatesExpand
Reversed-phase high-performance liquid chromatographic determination of nitroorganics in munitions wastewater
Concentrations of HMX, RDX, TNT, and 2,4-DNT are determined in munitions wastewater. Aqueous samples are diluted with an equal volume of 76/24 (v/v) methanol-acetonitrile, filtered through aExpand
Trace analysis of explosives by thermospray high-performance liquid chromatography—mass spectrometry
Abstract A series of explosives were analyzed by thermospray high-performance liquid chromatography—mass spectrometry (TSP-HPLC—MS). Both positive and negative ion spectra were acquired inExpand
Microbial transformation of 2,4,6-trinitrotoluene and other nitroaromatic compounds
TLDR
A variety of nitroaromatic compounds, including 2,4,6-trinitrotoluene (TNT), were reduced by hydrogen in the presence of enzyme preparations from Veillonella alkalescens, indicating the question of whether ferredoxin acts as a nonspecific reductase for nitroARomatic compounds remains unresolved. Expand
Metabolism of dinitrobenzenes by rat isolated hepatocytes.
  • P. Cossum, D. Rickert
  • Chemistry, Medicine
  • Drug metabolism and disposition: the biological fate of chemicals
  • 1985
TLDR
There are substantial isomeric differences in the aerobic metabolism of the DNBs by rat hepatic enzymes in hepatocytes and hepatic subcellular fractions isolated from male Fischer-344 rats. Expand
Metabolism and toxicity of dinitrobenzene isomers in erythrocytes from Fischer-344 rats, rhesus monkeys and humans.
TLDR
The data suggest that although the erythrocyte can conjugate DNB isomers with glutathione, this pathway offers no substantial protection from methemoglobinemia induced by dinitrobenzenes. Expand
The involvement of the gastro-intestinal microflora in nitro-compound-induced methaemoglobinaemia in rats and its relationship to nitrogroup reduction.
TLDR
Investigations into the methaemoglobinaemia-inducing capacity of three mono- and five dinitro-compounds in both normal and antibiotically pretreated rats in vivo, and in vitro on incubation with rat blood suggest that in some cases the conversion of haemoglobin to meethaemoglobin could occur possibly as a result of a direct interaction between unchanged nitro-Compounds and haememia. Expand
Comparison of extraction techniques for munitions residues in soil
Extraction of trinitrotoluene (TNT), trinitrobenzene (TNB), hexahydrotrinitrotriazine (RDX), and octahydrotetranitrotetrazocine (HMX) from two soils was studied in terms of process kinetics andExpand
Genotoxic activity in microorganisms of tetryl, 1,3-dinitrobenzene and 1,3,5-trinitrobenzene.
TLDR
In this segment of a programme initiated by military authorities, the genotoxic potential of three nitroaromatic compounds, which have found significant use in explosive preparations, has been demonstrated. Expand
...
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