Separation and elution order of the enantiomers of some β-agonists using polysaccharide-based chiral columns and normal phase eluents by high-performance liquid chromatography.

@article{Gumustas2016SeparationAE,
  title={Separation and elution order of the enantiomers of some β-agonists using polysaccharide-based chiral columns and normal phase eluents by high-performance liquid chromatography.},
  author={Mehmet Gumustas and Sibel A Ozkan and Bezhan Chankvetadze},
  journal={Journal of chromatography. A},
  year={2016},
  volume={1467},
  pages={
          297-305
        }
}
In this study separation of enantiomers of 8 chiral β-agonists were studied on 6 polysaccharide-based chiral columns in polar-organic and alcohol-hydrocarbon mobile phases. No separation of enantiomers was observed on any column with polar-organic mobile phase eluents such as pure methanol, ethanol or acetonitrile. Most of the chiral analytes were resolved into enantiomers when alcohol-hydrocarbon type mobile phases were used. The most successful column was Lux Cellulose-2 on which all 8 chiral… CONTINUE READING
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