Separation and determination of toxic pyrrolizidine alkaloids in traditional Chinese herbal medicines by micellar electrokinetic chromatography with organic modifier.

@article{Yu2005SeparationAD,
  title={Separation and determination of toxic pyrrolizidine alkaloids in traditional Chinese herbal medicines by micellar electrokinetic chromatography with organic modifier.},
  author={Lijun Yu and Yan Xu and Huatao Feng and Sam Fong Yau Li},
  journal={Electrophoresis},
  year={2005},
  volume={26 17},
  pages={3397-404}
}
A simple and rapid micellar electrokinetic chromatography (MEKC) method was developed for the separation and determination of four toxic pyrrolizidine alkaloids (PAs) (senkirkine, senecionine, retrorsine, and seneciphylline) in two traditional Chinese herbal medicines (Qian liguang and Kuan donghua). Separation was performed in the running buffer consisting… CONTINUE READING