Separating the direct effect of hypoxia from the indirect effect of changes in cardiac output on the maximum pressure difference across the tricuspid valve in healthy humans

@article{Balanos2005SeparatingTD,
  title={Separating the direct effect of hypoxia from the indirect effect of changes in cardiac output on the maximum pressure difference across the tricuspid valve in healthy humans},
  author={George Balanos and Nicholas Philip Talbot and Peter A. Robbins and Keith L. Dorrington},
  journal={Pfl{\"u}gers Archiv},
  year={2005},
  volume={450},
  pages={372-380}
}
In healthy humans, changes in cardiac output are commonly accommodated with minimal change in pulmonary artery pressure. Conversely, exposure to hypoxia is associated with substantial increases in pulmonary artery pressure. In this study we used non-invasive measurement of an index of pulmonary artery pressure, the maximum systolic pressure difference across the tricuspid valve (ΔPmax), to examine the pulmonary vascular response to changes in blood flow during both air breathing and hypoxia. We… CONTINUE READING
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Pulmonary circulation. From basic mechanisms to clinical practice

  • JMB Hughes, NW Morrell
  • 2001
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