Separated human breast epithelial and myoepithelial cells have different growth factor requirements in vitro but can reconstitute normal breast lobuloalveolar structure.

@article{Gomm1997SeparatedHB,
  title={Separated human breast epithelial and myoepithelial cells have different growth factor requirements in vitro but can reconstitute normal breast lobuloalveolar structure.},
  author={Jennifer J. Gomm and R. C. Coope and P. J. Browne and R C Coombes},
  journal={Journal of cellular physiology},
  year={1997},
  volume={171 1},
  pages={11-9}
}
In order to investigate the specific factors controlling the growth of normal breast cell types, purified populations of human breast epithelial and myoepithelial cells from reduction mammoplasties were grown in primary culture in three defined media and their response to foetal calf serum (FCS), epidermal growth factor (EGF) and basic fibroblast growth factor (FGF2) measured using MTT growth assays. Epithelial and myoepithelial cells differed markedly in their growth requirements. Whereas… CONTINUE READING

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