Separate roles of the latent and infectious periods in shaping the relation between the basic reproduction number and the intrinsic growth rate of infectious disease outbreaks.

@article{Yan2008SeparateRO,
  title={Separate roles of the latent and infectious periods in shaping the relation between the basic reproduction number and the intrinsic growth rate of infectious disease outbreaks.},
  author={Ping Wang Yan},
  journal={Journal of theoretical biology},
  year={2008},
  volume={251 2},
  pages={238-52}
}
Two approximations are commonly used to describe the spread of an infectious disease at its early phase: (i) the branching processes based on the generation concept and (ii) the exponential growth over calendar time. The former is characterized by a mean parameter: the reproduction number R(0). The latter is characterized by a growth rate rho, also known as the Malthusian number. It is common to use empirically observed rho to assess R(0) using formulae derived either when both the latent and… CONTINUE READING

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