Separate base usages of genes located on the leading and lagging strands in Chlamydia muridarum revealed by the Z curve method

@article{Guo2007SeparateBU,
  title={Separate base usages of genes located on the leading and lagging strands in Chlamydia muridarum revealed by the Z curve method},
  author={Feng-Biao Guo and Xiu-Juan Yu},
  journal={BMC Genomics},
  year={2007},
  volume={8},
  pages={366 - 366}
}
The nucleotide compositional asymmetry between the leading and lagging strands in bacterial genomes has been the subject of intensive study in the past few years. It is interesting to mention that almost all bacterial genomes exhibit the same kind of base asymmetry. This work aims to investigate the strand biases in Chlamydia muridarum genome and show the potential of the Z curve method for quantitatively differentiating genes on the leading and lagging strands. The occurrence frequencies of… CONTINUE READING

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