Separable arrowhead microneedles.

  title={Separable arrowhead microneedles.},
  author={Leonard Y. Chu and Mark R. Prausnitz},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  volume={149 3},
Hypodermic needles cause pain and bleeding, produce biohazardous sharp waste and require trained personnel. To address these issues, we introduce separable arrowhead microneedles that rapidly and painlessly deliver drugs and vaccines to the skin. These needles are featured by micron-size sharp tips mounted on blunt shafts. Upon insertion in the skin, the sharp-tipped polymer arrowheads encapsulating drug separate from their metal shafts and remain embedded in the skin for subsequent dissolution… CONTINUE READING

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