Sentinel node identification using microbubbles and contrast-enhanced ultrasonography.

  title={Sentinel node identification using microbubbles and contrast-enhanced ultrasonography.},
  author={Ali Rıza Sever and Philippa Mills and Sue C. Jones and Willem Mali and Peter A. Jones},
  journal={Clinical radiology},
  volume={67 7},
Sentinel lymph node (SLN) biopsy has become the recommended method for surgical staging of the axilla in patients with breast cancer. Grey-scale axillary ultrasonography (US) combined with US-guided biopsy is a widely used preoperative staging procedure but has limited sensitivity. US contrast agent "microbubbles", when injected intradermally, have been shown to have the potential to enter the breast lymphatics, travel rapidly to the axilla, and visualize the putative SLNs. This review… CONTINUE READING

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