Sentinel Node Metastasis in Patients with Breast Carcinoma Accurately Predicts Immunohistochemically Detectable Nonsentinel Node Metastasis

@article{Chu1999SentinelNM,
  title={Sentinel Node Metastasis in Patients with Breast Carcinoma Accurately Predicts Immunohistochemically Detectable Nonsentinel Node Metastasis},
  author={Kyo U. Chu and Roderick R. Turner and Nora M. Hansen and RN BSNMeghanB.Brennan and Armando E. Giuliano},
  journal={Annals of Surgical Oncology},
  year={1999},
  volume={6},
  pages={756-761}
}
Background: Sentinel lymphadenectomy is highly accurate for identifying axillary metastasis from a primary breast carcinoma. Nonsentinel axillary lymph nodes (NSNs) are unlikely to contain tumor cells if the axillary sentinel node (SN) is tumor free. We previously showed that the size of the primary tumor and the size of its SN metastasis predict the risk of NSN tumor involvement detected by hematoxylin and eosin staining. This study used immunohistochemical staining (IHC) to determine the… CONTINUE READING