Sensory neurotoxins: chemically induced selective destruction of primary sensory neurons.

@article{Jancs1981SensoryNC,
  title={Sensory neurotoxins: chemically induced selective destruction of primary sensory neurons.},
  author={G{\'a}bor Jancs{\'o} and Elizabeth Kir{\'a}ly},
  journal={Brain research},
  year={1981},
  volume={210 1-2},
  pages={83-9}
}
Neonatal capsaicin treatment has been shown to cause selective degeneration of chemosensitive primary sensory neurons involved in the mediation of chemogenic pain and in neurogenic inflammatory responses. In the present study the neurotoxic effect of capsaicin congeners was investigated in the newborn rat. Some quantitative data on the selective neurotoxic action of capsaicin are also reported. Electron microscopy indicates that some pungent congeners of capsaicin also induce the selective… CONTINUE READING