Sensory neuron diseases

  title={Sensory neuron diseases},
  author={Angelo Sghirlanzoni and Davide Pareyson and Giuseppe Lauria},
  journal={The Lancet Neurology},
Sensory Neuronopathy and Autoimmune Diseases
Clinical, neurophysiological, and therapeutic data on autoimmune disease-related SN, namely, in patients with Sjögren's syndrome, autoimmune hepatitis, and celiac disease are reviewed.
Sensory neuronopathies
The sensory neuronopathies (or ganglionopathies) are a small subcategory of neuropathies characterized by primary degeneration of the dorsal root ganglia and trigeminal ganglion sensory neurons,
Neuroimaging in Sensory Neuronopathy
The aim of this review is to gather available information on neuroimaging findings of SN, discuss their clinical correlates and the potential impact of novel MRI‐based techniques.
Sensory Neuronopathies
Even though sensory neuronopathies are rare, significant progress has been made regarding characterization of their clinical, electrophysiologic, and imaging features; this does not hold true, however, for treatment.
The dorsal root ganglion under attack: the acquired sensory ganglionopathies
The clinical and pathological features of acquired sensory ganglionopathies are discussed and a practical approach to their diagnosis and management is focused on.
The pattern and diagnostic criteria of sensory neuronopathy: a case–control study
In the study population, sensory neuronopathy showed a common clinical and electrophysiological pattern that was independent of the underlying cause, including unusual forms with only patchy sensory loss, mild electrical motor nerve abnormalities and predominant small fibre or isolated lower limb involvement.
Sensory neuronopathies: A case series and literature review
Sensory neuronopathies caused severe disability, especially in patients with generalised areflexia and pseudoathetosis, and with motor involvement and raised CSF protein by univariate analysis.


Clinical features and pathophysiological basis of sensory neuronopathies (ganglionopathies)
In SSN, early diagnosis by the detection of anti‐Hu antibodies and early treatment of the cancer gives the best chance of stabilizing the disorder and in SS sensory ganglionitis, response to treatment has been disappointing, but immunomodulating treatments are emerging.
Causes and Diagnosis of Sensory Neuropathies: A Review
  • H. Mitsumoto, A. Wilbourn
  • Medicine, Psychology
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
  • 1994
The electrophysiological features, laboratory findings, and nerve biopsy results in patients and discuss in detail the potential underlying diseases included in the differential diagnosis of sensory neuropathies.
Neurophysiological Diagnosis of Acquired Sensory Ganglionopathies
Investigation of chronic progressive ganglionopathy of different etiology found a widespread decrease in sensory nerve action potential amplitudes, which involved both upper and lower limb nerves, even in patients with asymmetrical or patchy clinical presentation.
Diagnosis of hereditary neuropathies in adult patients
  • D. Pareyson
  • Medicine, Psychology
    Journal of Neurology
  • 2003
Abstract. This paper reviews the clinical diagnostic approach to hereditary neuropathies in adults by analysing: elements that point to a neuropathy of inherited origin, different modalities of
Anti-Hu associated paraneoplastic sensory neuronopathy with upper motor neurone involvement
To the authors' knowledge, this is the first demonstration of upper motor neurone involvement in anti-Hu associated paraneoplatic syndrome.
Chronic immune sensory polyradiculopathy
The term chronic immune sensory polyradiculopathy (CISP) is suggested for this syndrome, which preferentially affects large myelinated fibers of the posterior roots, may respond favorably to treatment, and may be a restricted form of chronic inflammatory demyelinating poly Radiculoneuropathy.
Hereditary sensory neuropathies
This review will concentrate on the recent genetic advances in hereditary sensory and autonomic neuropathy, and especially on those forms that overlap clinically with Charcot-Marie-Tooth disease, hence the title of the review ‘Hereditary sensory neuropathies’.
Subacute sensory neuropathy: A remote effect of carcinoma
Seven patients with subacute sensory neuropathy are described and the findings in 29 previously reported patients are reviewed. The presence of this characteristic neurological disorder strongly
Hereditary sensory neuropathy with deafness
A 39-year-old woman with hereditary sensory neuropathy-type I (HSN-I) and deafness—Hicks' disease showed cell loss in the organ of Corti, and spiral ganglia and atrophy of acoustic nerves, which suggested that HSN-I with deafness is nosologically related to familial multi system atrophy.