Sensory input to primate spinal cord is presynaptically inhibited during voluntary movement

@article{Seki2003SensoryIT,
  title={Sensory input to primate spinal cord is presynaptically inhibited during voluntary movement},
  author={Kazuhiko Seki and Steve I. Perlmutter and Eberhard E. Fetz},
  journal={Nature Neuroscience},
  year={2003},
  volume={6},
  pages={1309-1316}
}
During normal voluntary movements, re-afferent sensory input continuously converges on the spinal circuits that are activated by descending motor commands. This time-varying input must either be synergistically combined with the motor commands or be appropriately suppressed to minimize interference. The earliest suppression could be produced by presynaptic inhibition, which effectively reduces synaptic transmission at the initial synapse. Here we report evidence from awake, behaving monkeys… CONTINUE READING
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