Sensory circumventricular organs and brain homeostatic pathways

@article{Johnson1993SensoryCO,
  title={Sensory circumventricular organs and brain homeostatic pathways},
  author={A. K. Johnson and P. Gross},
  journal={The FASEB Journal},
  year={1993},
  volume={7},
  pages={678 - 686}
}
Circumventricular organs (CVOs), small structures bordering the ventricular spaces in the midline of the brain, have common morphological and endocrine‐like characteristics that distinguish them from the rest of the nervous system. Among their unique features are cellular contacts with two fluid phases — blood and cerebrospinal fluid — and neural connections with strategic nuclei establishing circuitry for communications throughout the neuraxis. A variety of additional morphological and… Expand
Sensory circumventricular organs in health and disease
TLDR
This review highlights recent investigations that show that the CVOs and related structures are involved in pathological conditions such as sepsis, stress, trypanosomiasis, autoimmune encephalitis, systemic amyloidosis and prion infections, while detailed information on their role in other neurodegenerative diseases such as Alzheimer's disease or multiple sclerosis is lacking. Expand
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TLDR
The SFO and OVLT located, respectively, at the dorsal and ventral ends of the midline anterior wall of the third ventricle have important roles in osmoreception and autonomic function that are mediated by direct afferent and efferent neural connections with regions of the hypothalamus, midbrain and hindbrain influencing thirst, vasopressin secretion, and cardiovascular regulation. Expand
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CHAPTER 19 – Circumventricular Organs
The circumventricular organs (CVOs) of the human brain comprises of the subfornical organ (SFO), vascular organ of the lamina terminalis (OVLT), median eminence, neurohypophysis, pineal gland,Expand
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TLDR
This work is based on a unique set of histological preparations from 12 species of mammals and 5 species of birds, and is taking the form of an atlas to study the specific characteristics of the vascular architecture of the circumventricular organs. Expand
New aspects in fenestrated capillary and tissue dynamics in the sensory circumventricular organs of adult brains
  • S. Miyata
  • Biology, Medicine
  • Front. Neurosci.
  • 2015
TLDR
Recent advances have been discussed in fenestrated capillary characterization and dynamic tissue reconstruction accompanied by angiogenesis and neurogliogenesis in the sensory CVOs of adult brains. Expand
Vasopressin and sensory circumventricular organs.
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Anatomical Organization of the Rat Subfornical Organ
The subfornical organ (SFO) is a sensory circumventricular organ located along the anterodorsal wall of the third ventricle. SFO lacks a complete blood-brain barrier (BBB), and thusExpand
Anatomical, molecular and pathological consideration of the circumventricular organs.
TLDR
This study used LCM and microarrays to analyse the transcriptomes of three CVOs, the SCO, the subfornical organ (SFO) and the PG and the third ventricle ependyma of the adult rat, in order to better characterise these organs at the molecular level. Expand
Understanding How the Subcommissural Organ and Other Periventricular Secretory Structures Contribute via the Cerebrospinal Fluid to Neurogenesis
TLDR
Early and new evidence concerning the role(s) of the SCO, and the probable mechanisms by which SCO compounds can readily reach the neurogenic niche of the subventricular zone flowing with the CSF are brought into discussion. Expand
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TLDR
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