Sensory but not parasympathetic nerves are required for ocular vascular remodeling following chronic sympathectomy in rat.

@article{Steinle2003SensoryBN,
  title={Sensory but not parasympathetic nerves are required for ocular vascular remodeling following chronic sympathectomy in rat.},
  author={Jena J Steinle and Peter G Smith},
  journal={Autonomic neuroscience : basic & clinical},
  year={2003},
  volume={109 1-2},
  pages={34-41}
}
Choroidal vascularity increases following chronic sympathetic denervation in rats. The mechanisms of this remodeling are unclear. Since both nitric oxide and substance P/CGRP have been suggested as angiogenic factors in other targets, we hypothesized that sensory or parasympathetic nerves may also participate in ocular vascular remodeling. To test this hypothesis, sympathetic denervation was accomplished by superior cervical ganglionectomy. Sensory denervation was induced by subcutaneous… CONTINUE READING