Sensory afferents regenerated into dorsal columns after spinal cord injury remain in a chronic pathophysiological state.

Abstract

Axon regeneration after experimental spinal cord injury (SCI) can be promoted by combinatorial treatments that increase the intrinsic growth capacity of the damaged neurons and reduce environmental factors that inhibit axon growth. A prior peripheral nerve conditioning lesion is a well-established means of increasing the intrinsic growth state of sensory… (More)

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