Sensory Ciliogenesis in C. elegans: Assignment of IFT components into Distinct Modules Based on Transport and Phenotypic Profiles

Abstract

Sensory cilium biogenesis within C. elegans neurons depends upon the kinesin-2-dependent intraflagellar transport (IFT) of ciliary precursors associated with IFT particles to the axoneme tip. Here we analyzed the molecular organization of the IFT machinery by comparing the in vivo transport and phenotypic profiles of multiple proteins involved in IFT and… (More)

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