Sensorimotor neuropathy resembling CIDP in patients receiving FK506.

@article{Wilson1994SensorimotorNR,
  title={Sensorimotor neuropathy resembling CIDP in patients receiving FK506.},
  author={John R. Wilson and Robin A Conwit and Benjamin H. Eidelman and Thomas Starzl and Kareem M. Abu-Elmagd},
  journal={Muscle & nerve},
  year={1994},
  volume={17 5},
  pages={528-32}
}
FK506 is an important immunosuppressant that has shown great promise in the treatment of autoimmune diseases. Approximately 5% of patients receiving FK506 develop major central nervous system toxicity, but the peripheral nerves are usually spared. During 1990-1991, some 1000 patients received liver transplants under FK506 immunosuppression. Of these, 3 patients developed severe multifocal demyelinating sensorimotor polyneuropathy 2-10 weeks after initiation of FK506 therapy. Improvement… CONTINUE READING

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